Did You Know That Neck Cancer Uterine Depends On Oncogén e6?

Authors

  • Natasha Blanco University of the Andes (UTA)
  • Danmarys Hernández University of the Andes (UTA)
  • Jhon Cruz University of the Andes (UTA)
  • Marco Bastidas University of the Andes (UTA)
  • Militza Quintero University of the Andes (UTA)
  • Adriana Rodríguez University of the Andes (UTA)
  • Morelva Toro University of the Andes (UTA)
  • Juan Puig University of the Andes (UTA)

Keywords:

E6 oncogene, long control region, Papilloma Virus Human, HPV

Abstract

Uterine cancer is an important pathology in Venezuela. Infection with Human Papilloma Virus (HPV) is one of the main causes of mucosal cancer, along with other environmental or immunological factors. One of the most sensitive methods to determine the presence of the virus's DNA is the Polymerase Chain Reaction (PCR) technique. A theory formulated by several authors states that in a carcinogenic process there is integration of the genome of the virus in the genome of the host. Based on this, this study aims to examine samples of patients with high-grade intraepithelial lesions and carcinogenesis, where the MY09 / MY11 system could not detect the presence of the virus. This work presents the development of an HPV detection system that uses, as a target sequence, the LCR-E6 region.

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Published

2024-06-13

How to Cite

Blanco, N., Hernández, D., Cruz, J., Bastidas, M., Quintero, M., Rodríguez, A., Toro, M., & Puig, J. (2024). Did You Know That Neck Cancer Uterine Depends On Oncogén e6?. Observador Del Conocimiento, 2(2), 143–150. Retrieved from https://revistaoc.oncti.gob.ve/index.php/odc/article/view/576

Issue

Vol. 2 No. 2 (2014): february

Section

Artículos

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